Don't know if this helps, but on my winxp system as soon as I installed IE7 I couldn't get GP3 to load, went back to IE5 and all was good. Don't know if that would work with Vista, but worth a try.
before i got this pc i had IE7 too, and gp3 ran perfectly...now i have it too, but this time it doesnt even install...But i guess i'll have to try that too. Tnxs!